Lysophosphatidic acid increases soluble ST2 expression in mouse lung and human bronchial epithelial cells
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چکیده
منابع مشابه
Transgenic Expression of Human Lysophosphatidic Acid Receptor LPA2 in Mouse Intestinal Epithelial Cells Induces Intestinal Dysplasia
Lysophosphatidic acid (LPA) acts on LPA2 receptor to mediate multiple pathological effects that are associated with tumorigenesis. The absence of LPA2 attenuates tumor progression in rodent models of colorectal cancer, but whether overexpression of LPA2 alone can lead to malignant transformation in the intestinal tract has not been studied. In this study, we expressed human LPA2 in intestinal e...
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ژورنال
عنوان ژورنال: Cellular Signalling
سال: 2012
ISSN: 0898-6568
DOI: 10.1016/j.cellsig.2011.08.004